{"product_id":"recombinant-human-psph-protein-his-tag-pksh032897","title":"Recombinant Human PSPH Protein (His Tag) - PKSH032897","description":"\u003cp\u003eRecombinant Human PSPH Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032897-10, PKSH032897-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PSPH\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Phosphoserine Phosphatase; PSP; PSPase; L-3-Phosphoserine Phosphatase; O-Phosphoserine Phosphohydrolase; PSPH\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P78330\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P78330\u003c\/p\u003e\n\n\u003cp\u003eBackground: Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation; moderate psychomotor retardation and facial features suggestive of Williams syndrome.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Glu225\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 50mM Tris, 250mM NaCl, 50mM Imidazole, pH 8.5 .\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 26.1 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 29 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068761211059,"sku":"PKSH032897-10","price":385.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068761243827,"sku":"PKSH032897-50","price":735.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_eca3b99c-99cb-4fa0-902b-1e6dcf209638.png?v=1708597416","url":"https:\/\/afsbio.com\/products\/recombinant-human-psph-protein-his-tag-pksh032897","provider":"AFSBio Inc.","version":"1.0","type":"link"}