{"product_id":"recombinant-human-puma-bbc3-protein-his-tag-pdeh100035","title":"Recombinant Human PUMA\/BBC3 protein (His Tag) - PDEH100035","description":"\u003cp\u003eRecombinant Human PUMA\/BBC3 protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PDEH100035-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PUMA; BBC3\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: BBC 3; Bbc3; BBC3_HUMAN; BCL 2 binding component 3; Bcl-2-binding component 3; BCL2 binding component 3; JFY 1; JFY-1; JFY1; p53 up regulated modulator of apoptosis; p53 up-regulated modulator of apoptosis; p53 Upregulated Modulator of Apoptosis; PUMA alpha; PUMA\/JFY1\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eApplication: Immunogen\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9BXH1\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9BXH1-1\u003c\/p\u003e\n\n\u003cp\u003eBackground: Essential mediator of p53\/TP53-dependent and p53\/TP53-independent apoptosis . Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53\/TP53. Regulates ER stress-induced neuronal apoptosis.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Immunogen(E-AB-40332)\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met1-Asn193\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 20.1 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 20-24 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43104344211635,"sku":"PDEH100035-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_d857a3cb-656c-498d-9aed-e873bfab5ee2.png?v=1709294787","url":"https:\/\/afsbio.com\/products\/recombinant-human-puma-bbc3-protein-his-tag-pdeh100035","provider":"AFSBio Inc.","version":"1.0","type":"link"}