{"product_id":"recombinant-human-rac2-protein-his-tag-pdeh100344","title":"Recombinant Human Rac2 protein (His tag) - PDEH100344","description":"Recombinant Human Rac2 protein (His tag)\n\nSize: 100μg\n\nCatalogue Numbers: PDEH100344-100\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: Rac2\n\nTarget Synonym: EN-7; Gx; HSPC022; p21-Rac2\n\nUNIProt ID: P15153\n\nResearch Areas: Signal Transduction\n\nTarget Species: Human\n\nExpression Host: E.coli\n\nFusion Tag: N-His \u0026amp; C-His\n\nAccession: P15153\n\nBackground: Ras-related C3 botulinum toxin substrate 2 (Rac2) is a small G-protein belonging to the Ras subfamily of the GTPase family. Rac2 acts as an \" on \/ off\" switch for signal transduction cascades and motilities. When GDP is attached to the small G-protein, the enzyme is inactivated. Release of the GDP and replace of the GTP cativate the GTPasee. Rac2 remains active until the GTP is hydrolyzed to GDP. Rac2 is a hematopoietic-specific Rho family GTPase implicated as an important constituent of the NADPH oxidase complex and shares 92% amino acid identity with the ubiquitously expressed Rac1. The small G-protein Rac2 regulates the rearrangements of actin and membrane necessary for Fcy receptor-mediated phagocytosis by macrophages. Activated Rac2 binds to the p21-binding domain of PAK1 and this binding provided a basis for microscopic methods to localize activation of these G proteins inside cells.\n\nSequence: Met 1-Cys 189\n\nPurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\n\nFormulation: Lyophilized from sterile PBS, pH 7.4.\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\nPlease refer to the specific buffer information in the printed manual.\n\nReconstitution: Please refer to the printed manual for detailed information.\n\nEndotoxin: Please contact us for more information.\n\nCalculated MW: 20.68 kDa\n\nObserved MW: 25 kDa\n\nStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\n\nShipping: This product is provided as lyophilized powder which is shipped with ice packs.\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43083551146163,"sku":"PDEH100344-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_9d102eee-6b9f-497c-a5f5-af9b3da12447.png?v=1708944512","url":"https:\/\/afsbio.com\/products\/recombinant-human-rac2-protein-his-tag-pdeh100344","provider":"AFSBio Inc.","version":"1.0","type":"link"}