{"product_id":"recombinant-human-ramp3m33l-protein-rp00782lq","title":"Recombinant Human RAMP3(M33L) Protein - RP00782LQ","description":"\u003cp\u003eRecombinant Human RAMP3(M33L) Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00782LQ-10, RP00782LQ-20, RP00782LQ-50, RP00782LQ-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human RAMP3(M33L) Protein is produced by CHO Cells system. The target protein is expressed with sequence (Arg24-Val118) of Human RAMP3 (Accession #NP_005847.1) fused with His tag at the C-Terminus..\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: RAMP3, Receptor activity-modifying protein 3, RAMP3-H\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O60896\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10268\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -70°C. This product is stable at ≤ -70°C for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eBackground: RAMP3 belongs to the RAMP family. Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL), calcitonin receptor (CALCR) and G-protein coupled estrogen receptor 1 (GPER1).Required for the transport of CALCRL and GPER1 receptors to the plasma membrane.Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner.Together with CALCRL, form a receptor complex for adrenomedullin\/ADM and intermedin\/ADM2.Together with CALCR, act as a receptor complex for amylin\/IAPP.\u003c\/p\u003e\n\n\u003cp\u003eSource: CHO Cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-8×His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as 0.22μm filtered solution in PBS (pH 7.4).\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: RAGGCNETGLLERLPLCGKAFADMMGKVDVWKWCNLSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEV\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198244217011,"sku":"RP00782LQ-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198244249779,"sku":"RP00782LQ-20","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198244282547,"sku":"RP00782LQ-50","price":420.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198244315315,"sku":"RP00782LQ-100","price":672.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_9d4708c4-6e8b-4883-8bfe-cd986d8e0499.png?v=1766959656","url":"https:\/\/afsbio.com\/products\/recombinant-human-ramp3m33l-protein-rp00782lq","provider":"AFSBio Inc.","version":"1.0","type":"link"}