{"product_id":"recombinant-human-relt-tnfrsf19l-protein-his-fc-tag-pksh031544","title":"Recombinant Human RELT\/TNFRSF19L Protein (His \u0026 Fc Tag) - PKSH031544","description":"\u003cp\u003eRecombinant Human RELT\/TNFRSF19L Protein (His \u0026amp; Fc Tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSH031544-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: RELT, TNFRSF19L\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Tumor necrosis factor receptor superfamily member 19L, TNFRSF19L, Receptor expressed in lymphoid tissues, RELT\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction,\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His \u0026amp; Fc\u003c\/p\u003e\n\n\u003cp\u003eAccession: NP_116260.2\u003c\/p\u003e\n\n\u003cp\u003eBackground: Receptor expressed in lymphoid tissues (RELT), also known as tumor necrosis factor receptor superfamily, member 19-like (TNFRSF19L), is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1. RELT\/TNFRSF19L is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. RELT\/TNFRSF19L is a type I transmembrane glycoprotein with a cysteine-rich extracellular domain, possessing significant homology to other members of the TNFR superfamily, especially TNFRSF19, DR3, OX40, and LTbeta receptor. RELT\/TNFRSF19L is able to activate the NF-kappaB pathway and selectively binds tumor necrosis factor receptor-associated factor 1. RELT\/TNFRSF19L is able to activate the NF-\u0026amp;kappa, B pathway and selectively binds tumor necrosis factor receptor-associated factor 1. Although the soluble form of RELT fusion protein does not inhibit the one-way mixed lymphocyte reaction, immobilized RELT\/TNFRSF19L is capable of costimulating T-cell proliferation in the presence of CD3 signaling.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Ala 160\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 42 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 55-60 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43155038208179,"sku":"PKSH031544-100","price":1024.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b332986d-c41c-47b4-b252-6f1be263369c.png?v=1710437210","url":"https:\/\/afsbio.com\/products\/recombinant-human-relt-tnfrsf19l-protein-his-fc-tag-pksh031544","provider":"AFSBio Inc.","version":"1.0","type":"link"}