{"product_id":"recombinant-human-relt-tnfrsf19l-protein-his-tag-pksh031543","title":"Recombinant Human RELT\/TNFRSF19L Protein (His Tag) - PKSH031543","description":"Recombinant Human RELT\/TNFRSF19L Protein (His Tag)\n\nSize: 100μg\n\nCatalogue Number: PKSH031543-100\n\nCitations, Manuals and MSDS Available upon request.\n\nAbbreviation: RELT; TNFRSF19L\n\nTarget Symptom: Tumor necrosis factor receptor superfamily member 19L; TNFRSF19L; Receptor expressed in lymphoid tissues; RELT\n\nResearch Area: Signal Transduction; \n\nTarget Species: Human\n\nExpression Host: HEK293 Cells\n\nFusion Tag: C-His\n\nAccession: NP_116260.2\n\nBackground: Receptor expressed in lymphoid tissues (RELT); also known as tumor necrosis factor receptor superfamily; member 19-like (TNFRSF19L); is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1. RELT\/TNFRSF19L is capable of stimulating T-cell proliferation in the presence of CD3 signaling; which suggests its regulatory role in immune response. RELT\/TNFRSF19L is a type I transmembrane glycoprotein with a cysteine-rich extracellular domain; possessing significant homology to other members of the TNFR superfamily; especially TNFRSF19; DR3; OX40; and LTbeta receptor. RELT\/TNFRSF19L is able to activate the NF-kappaB pathway and selectively binds tumor necrosis factor receptor-associated factor 1. RELT\/TNFRSF19L is able to activate the NF-κ B pathway and selectively binds tumor necrosis factor receptor-associated factor 1. Although the soluble form of RELT fusion protein does not inhibit the one-way mixed lymphocyte reaction; immobilized RELT\/TNFRSF19L is capable of costimulating T-cell proliferation in the presence of CD3 signaling.\n\nSequence: Met 1-Ala 160\n\nPurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\n\nFormulation: Lyophilized from sterile PBS, pH 7.4\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\nPlease refer to the specific buffer information in the printed manual.\n\nReconstitution: Please refer to the printed manual for detailed information.\n\nEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\n\nCalculated MW: 15.7 kDa\n\nStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\n\nShipping: This product is provided as lyophilized powder which is shipped with ice packs.\n\nResearch Use Only","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43107364864179,"sku":"PKSH031543-100","price":1024.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_5d183581-be7a-41d7-9d6b-570efc522805.png?v=1709382809","url":"https:\/\/afsbio.com\/products\/recombinant-human-relt-tnfrsf19l-protein-his-tag-pksh031543","provider":"AFSBio Inc.","version":"1.0","type":"link"}