{"product_id":"recombinant-human-retinol-binding-protein-4-prbp-protein-rp00284","title":"Recombinant Human Retinol-binding protein 4\/PRBP Protein - RP00284","description":"\u003cp\u003eRecombinant Human Retinol-binding protein 4\/PRBP Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00284-10, RP00284-20, RP00284-50, RP00284-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Retinol-binding protein 4\/PRBP Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Glu19-Leu201) of human RBP4 (Accession #NP_006735.2) fused with an Fc, 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: MCOPCB10, RDCCAS, RBP4, RDCCAS\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P02753\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5950\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Human RBP4 Protein at 2 μg\/mL (100 μL\/well) can bind RBP4 Rabbit mAb with a linear range of 0.12-2.1 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-hFc\u0026amp;His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: ERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYCDGRSERNLL\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198303494323,"sku":"RP00284-10","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198303527091,"sku":"RP00284-20","price":266.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198303559859,"sku":"RP00284-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198303592627,"sku":"RP00284-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_fa1ff501-1d1e-4784-bc4e-25520a9acab4.png?v=1766960359","url":"https:\/\/afsbio.com\/products\/recombinant-human-retinol-binding-protein-4-prbp-protein-rp00284","provider":"AFSBio Inc.","version":"1.0","type":"link"}