{"product_id":"recombinant-human-ribonuclease-k6-rnase6-protein-his-tag-pksh033003","title":"Recombinant Human Ribonuclease K6\/RNASE6 Protein (His Tag) - PKSH033003","description":"\u003cp\u003eRecombinant Human Ribonuclease K6\/RNASE6 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033003-10, PKSH033003-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Ribonuclease K6; RNASE6\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Ribonuclease K6; RNase K6; RNASE6; RNS6\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q93091\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: epigenetics and nuclear signal\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q93091\u003c\/p\u003e\n\n\u003cp\u003eBackground: Ribonuclease K6 (RNASE6) is a secreted protein that belongs to the pancreatic ribonuclease family. Human RNASE6 is synthesized as a 150 amino acid precursor that contains a 23 amino acid signal sequence, and a 127 amino acid mature chain. RNASE6 is expressed in many tissues, with high expression levels in the lung, with lower expression levels in the heart, placenta, kidney, pancreas, liver, brain, and skeletal muscle. It is also detected in monocytes and neutrophils. RNASE6 may have a role in host defense.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Trp24-Leu150\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mMDTT, 10%Glycerol, pH7.5.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 15.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 22 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068794372275,"sku":"PKSH033003-10","price":385.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068794405043,"sku":"PKSH033003-50","price":735.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e353ad98-6a40-4ea8-b542-a0f42698384d.png?v=1708597679","url":"https:\/\/afsbio.com\/products\/recombinant-human-ribonuclease-k6-rnase6-protein-his-tag-pksh033003","provider":"AFSBio Inc.","version":"1.0","type":"link"}