{"product_id":"recombinant-human-sema4b-c-fc-6his-ept019","title":"Recombinant Human SEMA4B (C-Fc-6His) - EPT019","description":"\u003cp\u003eRecombinant Human SEMA4B (C-Fc-6His)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: EPT019-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Semaphorin-4B is a single-pass type I membrane protein. SEMA4B is a member of the semaphorin family. The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Semaphorin-4B; KIAA1745; SEMAC; SEMA4B\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Semaphorin 4B is produced by our Mammalian expression system and the target gene encoding Leu39-Glu712 is expressed with a Fc, 6His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9NPR2\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 102 KDa\u003c\/p\u003e\n\n\u003cp\u003eApparent Molecular Weight: 114 KDa, reducing conditions\u003c\/p\u003e\n\n\u003cp\u003eStorage Condition: Lyophilized protein should be stored at \u0026lt; -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20°C for 3 months.\u003c\/p\u003e\n\n\u003cp\u003ePurity: Greater than 95% as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 0.1 ng\/µg (1 EU\/µg) as determined by LAL test.\u003c\/p\u003e\n\n\u003cp\u003eRedissolve: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg\/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. \u003c\/p\u003e\n\n\u003cp\u003eDelivery Condition: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized protein should be stored at \u0026lt; -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20°C for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"Default Title","offer_id":43211013324979,"sku":"EPT019-50","price":1146.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_7194f4f9-99b6-4886-8035-36331669709a.png?v=1767117596","url":"https:\/\/afsbio.com\/products\/recombinant-human-sema4b-c-fc-6his-ept019","provider":"AFSBio Inc.","version":"1.0","type":"link"}