{"product_id":"recombinant-human-semaphorin-3a-sema3a-protein-his-flag-tag-pksh033535","title":"Recombinant Human Semaphorin 3A\/SEMA3A Protein (His \u0026 Flag Tag) - PKSH033535","description":"\u003cp\u003eRecombinant Human Semaphorin 3A\/SEMA3A Protein (His \u0026amp; Flag Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033535-10, PKSH033535-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Semaphorin 3A; SEMA3A\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Semaphorin III; SEMA3A; SEMAD; Hsema-I; SEMA1; SemD; Semad; coll-1; Hsema-III; Sema III\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Cardiovascular; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His-Flag\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q14563\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q14563\u003c\/p\u003e\n\n\u003cp\u003eBackground: emaphorin-3A is a secreted protein which belongs to the semaphorin family. Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 500 aa Sema domain.This protein can function as either a chemorepulsive agent; inhibiting axonal outgrowth; or as a chemoattractive agent; stimulating the growth of apical dendrites. In both cases; the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Lys26-Phe546\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 61.3 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 70-75 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113966862515,"sku":"PKSH033535-10","price":180.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113966895283,"sku":"PKSH033535-50","price":525.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_1f1edc75-b8c5-48ed-b01c-a526e17684ec.png?v=1709549310","url":"https:\/\/afsbio.com\/products\/recombinant-human-semaphorin-3a-sema3a-protein-his-flag-tag-pksh033535","provider":"AFSBio Inc.","version":"1.0","type":"link"}