{"product_id":"recombinant-human-senp2-protein-his-tag-sumo-tag-pksh033026","title":"Recombinant Human SENP2 Protein (His Tag, SUMO Tag) - PKSH033026","description":"\u003cp\u003eRecombinant Human SENP2 Protein (His Tag, SUMO Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033026-10, PKSH033026-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SENP2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Sentrin-specific protease 2; Axam2; SMT3-specific isopeptidase 2; Sentrin\/SUMO-specific protease SENP2; KIAA1331; SENP2.\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9HC62\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell biology; epigenetics and nuclear signal\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9HC62\u003c\/p\u003e\n\n\u003cp\u003eBackground: SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Asp363-Leu589\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 50mM HEPES, 5% Glycerol, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 26.8 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 29 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068801319091,"sku":"PKSH033026-10","price":260.4,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068801351859,"sku":"PKSH033026-50","price":359.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4e47183d-eaef-49f0-8527-8f85ea949141.png?v=1708597728","url":"https:\/\/afsbio.com\/products\/recombinant-human-senp2-protein-his-tag-sumo-tag-pksh033026","provider":"AFSBio Inc.","version":"1.0","type":"link"}