{"product_id":"recombinant-human-serpin-g1-plasma-protease-c1-inhibitor-protein-rp00197","title":"Recombinant Human Serpin G1\/Plasma protease C1 inhibitor Protein - RP00197","description":"\u003cp\u003eRecombinant Human Serpin G1\/Plasma protease C1 inhibitor Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00197-10, RP00197-20, RP00197-50, RP00197-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human SerpinG1\/C1 inhibitor\/C1IN Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Ala500) of human SerpinG1\/C1 inhibitor\/C1IN (Accession #NP_000053.2) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: SERPING1, C1IN, C1INH, C1NH, HAE1, HAE2, serpin family G member 1, C1IN, C1INH, C1NH, HAE1, HAE2\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P05155\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 710\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin).Serpin G1\/C1 inhibitor is the physiological inhibitor of activated C1r and C1s and regulates activation of both the complement and contact systems. Deficiency of C1 inhibitor results in hereditary angioedema, which is characterized by recurrent episodes of localized angioedema of the skin, gastrointestinal mucosa or upper respiratory mucosa. C1 inhibitor may prove useful in a variety of other diseases including septic shock, reperfusion injury, hyperacute transplant rejection, traumatic and hemorrhagic shock, and the increased vascular permeability associated with thermal injury, interleukin-2 therapy and cardiopulmonary bypass.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPILEVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTGSFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDPRA\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198235664563,"sku":"RP00197-10","price":182.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198235697331,"sku":"RP00197-20","price":154.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198235730099,"sku":"RP00197-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198235762867,"sku":"RP00197-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_1397d05e-e034-4283-9670-1f7e7f8ca165.png?v=1766959559","url":"https:\/\/afsbio.com\/products\/recombinant-human-serpin-g1-plasma-protease-c1-inhibitor-protein-rp00197","provider":"AFSBio Inc.","version":"1.0","type":"link"}