{"product_id":"recombinant-human-sgsh-protein-his-tag-pksh032823","title":"Recombinant Human SGSH Protein (His Tag) - PKSH032823","description":"\u003cp\u003eRecombinant Human SGSH Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH032823-10, PKSH032823-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SGSH\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: N-Sulphoglucosamine Sulphohydrolase; Sulfoglucosamine Sulfamidase; Sulphamidase; SGSH; HSS\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P51688\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Tags \u0026amp; Cell Markers; Neuroscience;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P51688\u003c\/p\u003e\n\n\u003cp\u003eBackground: N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Arg21-Leu502\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM GaCl2, 10%Glycerol, pH7.5.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 55.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 63 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068737650867,"sku":"PKSH032823-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068737683635,"sku":"PKSH032823-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e54ae899-64a6-4ac4-b62d-c2bcd531e7dc.png?v=1708597255","url":"https:\/\/afsbio.com\/products\/recombinant-human-sgsh-protein-his-tag-pksh032823","provider":"AFSBio Inc.","version":"1.0","type":"link"}