{"product_id":"recombinant-human-sod2-mn-sod-protein-his-tag-human-cells-pksh033071","title":"Recombinant Human SOD2\/Mn-SOD Protein (His Tag, Human Cells) - PKSH033071","description":"\u003cp\u003eRecombinant Human SOD2\/Mn-SOD Protein (His Tag, Human Cells)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033071-10, PKSH033071-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: SOD2; Mn-SOD\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Superoxide Dismutase [Mn] Mitochondrial; SOD2\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P04179\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Cell biology; Cardiovascular; Neuroscience; Cancer; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P04179\u003c\/p\u003e\n\n\u003cp\u003eBackground: Superoxide Dismutase (SOD2) belongs to the iron\/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide; a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer; while SOD2 is one of the primary enzymes that directly convert potential harmful oxidizing species to harmless metabolites.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Lys25-Lys222\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris; 150mM NaCl; pH8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 23.2 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 25 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068815540403,"sku":"PKSH033071-10","price":368.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068815573171,"sku":"PKSH033071-50","price":625.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_d3e25910-95f6-41e1-8145-0ac5116ddd4d.png?v=1708597853","url":"https:\/\/afsbio.com\/products\/recombinant-human-sod2-mn-sod-protein-his-tag-human-cells-pksh033071","provider":"AFSBio Inc.","version":"1.0","type":"link"}