{"product_id":"recombinant-human-st6gal1-protein-his-tag-pksh033362","title":"Recombinant Human ST6GAL1 Protein (His Tag) - PKSH033362","description":"\u003cp\u003eRecombinant Human ST6GAL1 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033362-10, PKSH033362-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ST6GAL1\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Beta-Galactoside Alpha-2; 6-Sialyltransferase 1; Alpha 2; 6-ST 1; B-Cell Antigen CD75; CMP-N-Acetylneuraminate-Beta-Galactosamide-Alpha-2; 6-Sialyltransferase 1; ST6Gal I; ST6GalI; Sialyltransferase 1; ST6GAL1; SIAT1\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; immunology;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P15907\u003c\/p\u003e\n\n\u003cp\u003eAccession: P15907\u003c\/p\u003e\n\n\u003cp\u003eBackground: The ST6GAL1 gene encodes β-Galactosamide α-2; 6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2; 6-sialylation of Galβ1; 4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Lys27-Cys406\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 44.6 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 41-48 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113952542899,"sku":"PKSH033362-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113952575667,"sku":"PKSH033362-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b1799247-a216-4662-bc06-46ab095744a9.png?v=1709549120","url":"https:\/\/afsbio.com\/products\/recombinant-human-st6gal1-protein-his-tag-pksh033362","provider":"AFSBio Inc.","version":"1.0","type":"link"}