{"product_id":"recombinant-human-tetherin-bst2-protein-his-tag-pksh033296","title":"Recombinant Human Tetherin\/BST2 Protein (His Tag) - PKSH033296","description":"\u003cp\u003eRecombinant Human Tetherin\/BST2 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033296-10, PKSH033296-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Tetherin; BST2\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Bone Marrow Stromal Antigen 2; BST-2; HM1.24 Antigen; Tetherin; CD317; BST2\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; Tags \u0026amp; Cell Markers; Cardiovascular; epigenetics and nuclear signal; immunology; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q10589\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q10589\u003c\/p\u003e\n\n\u003cp\u003eBackground: Bone Marrow Stromal Antigen 2 (BST2) is a single-pass type II membrane protein that belongs to the tetherin family. BST2 is predominantly expressed in the liver; lung; heart and placenta. BST2 is involved in the sorting of secreted proteins. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. BST2 is initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu; it has also been shown to inhibit the release of other viruses such as retroviruses; filoviruses; arenaviruses; and herpes viruses. BST2 may play a role in B-cell activation in rheumatoid arthritis.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Asn49-Ser161\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 13.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 23 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113943564467,"sku":"PKSH033296-10","price":180.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113943597235,"sku":"PKSH033296-50","price":525.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_0e264dc5-822a-4cb0-8f5c-35807134f176.png?v=1709549017","url":"https:\/\/afsbio.com\/products\/recombinant-human-tetherin-bst2-protein-his-tag-pksh033296","provider":"AFSBio Inc.","version":"1.0","type":"link"}