{"product_id":"recombinant-human-thioredoxin-sasp-txn-protein-rp00036","title":"Recombinant Human Thioredoxin\/SASP\/TXN Protein - RP00036","description":"\u003cp\u003eRecombinant Human Thioredoxin\/SASP\/TXN Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00036-10, RP00036-20, RP00036-50, RP00036-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human Thioredoxin\/SASP\/TXN Protein is produced by E. coli expression system. The target protein is expressed with sequence (Val2-Val105) of human Thioredoxin (Accession #NP_003320.2) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: TRDX, TRX, TRX1, TXN, TRX, TRX1\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P10599\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 7295\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein which belongs to the thioredoxin family. Trx-1 is the only extracellular occurring thioredoxin, and is secreted by lymphocytes, hepatocytes, fibroblasts, and several tumor cells. Plasma concentrations of Trx-1 are up to 6 nM. In cells, Trx-1 is localized predominantly in the cytoplasm. Small amounts have been detected in the nucleus and in association with the outside surface of the cells. Biological functions of Trx-1 include growth factor activity, antioxidant properties, a cofactor that provides reducing equivalents, and transcriptional regulation.\u003c\/p\u003e \n\n\u003cp\u003eBio-Activity: 1.Measured by its binding ability in a functional ELISA. Immobilized Human TXN Protein at 1 μg\/mL (100 μL\/well) can bind TXN Rabbit mAb with a linear range of 0.976-5.3 ng\/mL.|2.Measured by its ability to catalyze the reduction of insulin. The reaction leads to precipitation, which can be measured by absorbance at 650 nm. The specific activity is \u0026gt;9 A650\/min\/mg.\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198292156595,"sku":"RP00036-10","price":140.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198292189363,"sku":"RP00036-20","price":154.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198292222131,"sku":"RP00036-50","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198292254899,"sku":"RP00036-100","price":280.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_280b2745-28a2-45aa-9176-bc0229ee9de2.png?v=1766960212","url":"https:\/\/afsbio.com\/products\/recombinant-human-thioredoxin-sasp-txn-protein-rp00036","provider":"AFSBio Inc.","version":"1.0","type":"link"}