{"product_id":"recombinant-human-tigit-protein-rp00080","title":"Recombinant Human TIGIT Protein - RP00080","description":"\u003cp\u003eRecombinant Human TIGIT Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00080-10, RP00080-20, RP00080-50, RP00080-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human TIGIT Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Met22-Pro141) of human TIGIT (Accession #NP_776160.2) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: VSIG9, VSTM3, WUCAM, TIGIT\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q495A1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 201633\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This protein is a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The protein is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Human TIGIT at 1.5 μg\/mL (100 μL\/well) can bind Human CD155 with a linear range of 0.15-1.2 μg\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: MMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGTYTGRIFLEVLESSVAEHGARFQIP\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198296383667,"sku":"RP00080-10","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198296416435,"sku":"RP00080-20","price":266.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198296449203,"sku":"RP00080-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198296481971,"sku":"RP00080-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_de5fd224-3fa4-45b6-ad75-fd523b8dbb4a.png?v=1766960266","url":"https:\/\/afsbio.com\/products\/recombinant-human-tigit-protein-rp00080","provider":"AFSBio Inc.","version":"1.0","type":"link"}