{"product_id":"recombinant-human-timp-4-timp4-protein-his-tag-pksh033119","title":"Recombinant Human TIMP-4\/TIMP4 Protein (His Tag) - PKSH033119","description":"\u003cp\u003eRecombinant Human TIMP-4\/TIMP4 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033119-10, PKSH033119-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TIMP-4; TIMP4\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Metalloproteinase inhibitor 4; TIMP-4; Tissue inhibitor of metalloproteinases 4; TIMP4\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q99727\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell biology; Cardiovascular; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q99727\u003c\/p\u003e\n\n\u003cp\u003eBackground: Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene, belongs to the protease inhibitor I35 (TIMP) family. The protein complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Cys30-Pro224\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 23.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 20-24 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43068826288307,"sku":"PKSH033119-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43068826321075,"sku":"PKSH033119-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_cf049d5f-3f6e-49af-b815-c7591eb17b84.png?v=1708597946","url":"https:\/\/afsbio.com\/products\/recombinant-human-timp-4-timp4-protein-his-tag-pksh033119","provider":"AFSBio Inc.","version":"1.0","type":"link"}