{"product_id":"recombinant-human-tlk1-pku-beta-protein-his-gst-tagactive-pksh030339","title":"Recombinant Human TLK1\/PKU-beta Protein (His \u0026 GST Tag)(Active) - PKSH030339","description":"\u003cp\u003eRecombinant Human TLK1\/PKU-beta Protein (His \u0026amp; GST Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSH030339-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TLK1; PKU-beta\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: KIAA0137; PKU-beta\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: Baculovirus-Insect Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: Enzyme\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His \u0026amp; GST\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9UKI8\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q9UKI8-1\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a serine\/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eActivity: The specific activity was determined to be 1. 6 nmol\/min\/mg using Histone H3 protein as substrate.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Tyr 766\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 88 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as sterile solution of 20mM Tris, 500mM NaCl, pH 7.4, 10% glycerol\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 114 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 125 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43104347521203,"sku":"PKSH030339-50","price":1003.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_86e5dd34-ff9b-4a8b-b545-322f16b30409.png?v=1709294872","url":"https:\/\/afsbio.com\/products\/recombinant-human-tlk1-pku-beta-protein-his-gst-tagactive-pksh030339","provider":"AFSBio Inc.","version":"1.0","type":"link"}