{"product_id":"recombinant-human-tnf-beta-protein-rp01977","title":"Recombinant Human TNF-beta Protein - RP01977","description":"\u003cp\u003eRecombinant Human TNF-beta Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01977-10, RP01977-20, RP01977-50, RP01977-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human TNF-beta Protein is produced by CHO Cells expression system. The target protein is expressed with sequence (Leu35-Leu205) of Human TNF-beta(Accession #NP_000586.2) fused with His at the C-terminus..\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: LTA, TNFB, TNFSF1, Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P01374\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4049\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tumor Necrosis Factor β (TNF- β ) is a secreted protein belonging to the tumor necrosis factor family. TNF- βbinds to TNFRSF1A\/TNFR1, TNFRSF1B\/TNFBR and TNFRSF14\/HVEM in homotrimeric form, binds toTNFRSF3\/LTBR in heterotrimeric form with LTB. TNF- β forms heterotrimers with lymphotoxin-beta, whichanchors TNF- β to the cell surface. TNF- β mediates the inflammatory, immunostimulatory, and antiviralresponse, involves in the formation of second lymphoid organs during development, has a role in apoptosis.TNF-β is produced by lymphocytes and cytotoxic for a variety of tumor cells in vitro and in vivo.\u003c\/p\u003e\n\n\u003cp\u003eSource: CHO Cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: LPGVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAFAL\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.01 EU\/μg of the protein by LAL method\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198272790707,"sku":"RP01977-10","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198272823475,"sku":"RP01977-20","price":266.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198272856243,"sku":"RP01977-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198272889011,"sku":"RP01977-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_14b5749e-ceeb-480e-b132-72832d53c2c8.png?v=1766959975","url":"https:\/\/afsbio.com\/products\/recombinant-human-tnf-beta-protein-rp01977","provider":"AFSBio Inc.","version":"1.0","type":"link"}