{"product_id":"recombinant-human-tnfrsf10d-dcr2-trail-r4-cd264-protein-rp00992","title":"Recombinant Human TNFRSF10D\/DcR2\/TRAIL-R4\/CD264 Protein - RP00992","description":"\u003cp\u003eRecombinant Human TNFRSF10D\/DcR2\/TRAIL-R4\/CD264 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00992-10, RP00992-20, RP00992-50, RP00992-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Active Recombinant Human TNFRSF10D\/DcR2\/TRAIL-R4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala 56 - His 211 ) of human DcR2 (Accession #NP_003831.2) fused with an Fc, 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD, TNFRSF10D, DCR2, TRAIL-R4, TRAILR4, TRUNDD\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9UBN6\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 8793\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: 1.Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human TRAIL at 2 μg\/mL (100 μL\/well) can bind Recombinant Human DcR2 with a linear range of 15-60 ng\/mL.|2.Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL. The ED50 for this effect is 1.8-7.2 ng\/mL in the presence of 20 ng\/mL Recombinant Human TRAIL\/TNFSF10.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-hFc\u0026amp;His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: ATIPRQDEVPQQTVAPQQQRRSLKEEECPAGSHRSEYTGACNPCTEGVDYTIASNNLPSCLLCTVCKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKCKNESAASSTGKTPAAEETVTTILGMLASPYH\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198287831219,"sku":"RP00992-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198287863987,"sku":"RP00992-20","price":189.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198287896755,"sku":"RP00992-50","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198287929523,"sku":"RP00992-100","price":336.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_7f2b0f09-2bec-4e6c-849d-9d9d7eb41d67.png?v=1766960162","url":"https:\/\/afsbio.com\/products\/recombinant-human-tnfrsf10d-dcr2-trail-r4-cd264-protein-rp00992","provider":"AFSBio Inc.","version":"1.0","type":"link"}