{"product_id":"recombinant-human-tnfsf13b-baff-cd257-protein-rp00018","title":"Recombinant Human TNFSF13B\/BAFF\/CD257 Protein - RP00018","description":"\u003cp\u003eRecombinant Human TNFSF13B\/BAFF\/CD257 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP00018-10, RP00018-20, RP00018-50, RP00018-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Human TNFSF13B\/BAFF\/CD257 Protein is produced by E. coli expression system. The target protein is expressed with sequence ( Ala134-Leu285) of human TNFSF13B (Accession #NP_006564.1).\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: TNFSF13B, BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, TNLG7A, ZTNF4\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9Y275\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10673\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B\/TACI, TNFRSF17\/BCMA, and TNFRSF13C\/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells.\u003c\/p\u003e \n\n\u003cp\u003eBio-Activity: 1.Measured by its binding ability in a functional ELISA. Immobilized recombinant human BAFF at 5 μg\/mL (100 μL\/well) can bind recombinant human BCMA with a linear range of 3-20 ng\/mL.|2.Measured in a cell proliferation assay using anti-IgM stimulated mouse B cells. The ED50 for this effect is 0.1-1 ng\/mL, corresponding to a specific activity of 1×10^6 -1×10^7units\/mg. 3.Loaded Human TNFRSF17\/BCMA\/CD269 Protein, C-hFc\u0026amp;His (Catalog: RP00155) on ProA Biosensor, can bind Human TNFSF13B\/BAFF\/CD257 Protein, no Tag (Catalog: RP00018) with an affinity constant of 3.05nM as determined in BLI assay (Gator).\u003c\/p\u003e\n\n\u003cp\u003eSource: E. coli\u003c\/p\u003e\n\n\u003cp\u003eTag: No tag\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of 50mM Tris, 150mM NaCl, pH 8.0.Contact us for customized product form or formulation.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: AVQGPEETVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETGYFFIYGQVLYTDKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLPNNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKLL\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198291763379,"sku":"RP00018-10","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198291796147,"sku":"RP00018-20","price":266.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198291828915,"sku":"RP00018-50","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198291861683,"sku":"RP00018-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_7a6e3b77-5fcb-4ac7-af92-26e353d9eb2f.png?v=1766960208","url":"https:\/\/afsbio.com\/products\/recombinant-human-tnfsf13b-baff-cd257-protein-rp00018","provider":"AFSBio Inc.","version":"1.0","type":"link"}