{"product_id":"recombinant-human-tnfsf4-ox40l-protein-mfc-tag-pksh033572","title":"Recombinant Human TNFSF4\/OX40L Protein (mFc Tag) - PKSH033572","description":"\u003cp\u003eRecombinant Human TNFSF4\/OX40L Protein (mFc Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033572-10, PKSH033572-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TNFSF4; OX40L\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Tumor necrosis factor ligand superfamily member 4; Glycoprotein Gp34; OX40 ligand; OX40L; TAX transcriptionally-activated glycoprotein 1; TNFSF4; CD252; TXGP1; CD134L; CD252; GP34; OX-40; TXGP1\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: immunology; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-mFc\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P23510\u003c\/p\u003e\n\n\u003cp\u003eAccession: P23510\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tumor necrosis factor ligand superfamily member 4(TNFSF4\/OX40L) is a single-pass type II membrane protein. OX40L is expressed on the surface of activated B cells; T cells; dendritic cells and endothelial cells. OX40L binds to OX40(CD134); a member of the TNF receptor superfamily that is expressed predominantly on activated CD4+ T cells. OX40-OX40L co-stimulates signal to promote the survival and proliferation of activated CD4+ T cells and prolong the immune response. It involved in T-cell proliferation and cytokine production. Additional; it has been found association with systemic lupus erythematosus; no association with occurrence of atherosclerosis.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Gln51-Leu183\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 42.2 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 50-70 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113970368691,"sku":"PKSH033572-10","price":180.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113970401459,"sku":"PKSH033572-50","price":525.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_3c4df90e-0874-4a48-a841-0a5e779bcff1.png?v=1709549389","url":"https:\/\/afsbio.com\/products\/recombinant-human-tnfsf4-ox40l-protein-mfc-tag-pksh033572","provider":"AFSBio Inc.","version":"1.0","type":"link"}