{"product_id":"recombinant-human-trail-r3-tnfrsf10c-protein-fc-his-tag-pksh033129","title":"Recombinant Human TRAIL R3\/TNFRSF10C Protein (Fc \u0026 His Tag) - PKSH033129","description":"\u003cp\u003eRecombinant Human TRAIL R3\/TNFRSF10C Protein (Fc \u0026amp; His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033129-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TRAIL R3; TNFRSF10C\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Tumor Necrosis Factor Receptor Superfamily Member 10C; Antagonist Decoy Receptor for TRAIL\/Apo-2L; Decoy TRAIL Receptor Without Death Domain; Decoy Receptor 1; DcR1; Lymphocyte Inhibitor of TRAIL; TNF-Related Apoptosis-Inducing Ligand Receptor 3; TRAIL Receptor 3; TRAIL-R3; TRAIL Receptor Without an Intracellular Domain; CD263; TNFRSF10C; DCR1; LIT; TRAILR3; TRID\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O14798\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell biology; Cancer; immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: O14798\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains; lacks the intracellular signaling domain. As a result; binding of TRAIL to TRAIL R3 doesn’t transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and\/or TRAIL R2 from TRAIL-induced apoptosis.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala26-Ala221\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 48.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 90 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μg","offer_id":43068829106355,"sku":"PKSH033129-50","price":249.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_0494b74c-dc3e-4d1b-b75a-866e8cad3a9d.png?v=1708597971","url":"https:\/\/afsbio.com\/products\/recombinant-human-trail-r3-tnfrsf10c-protein-fc-his-tag-pksh033129","provider":"AFSBio Inc.","version":"1.0","type":"link"}