{"product_id":"recombinant-human-trkb-ntrk2-protein-his-tagactive-pksh033579","title":"Recombinant Human TrkB\/NTRK2 Protein (His Tag)(Active) - PKSH033579","description":"\u003cp\u003eRecombinant Human TrkB\/NTRK2 Protein (His Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSH033579-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TrkB; NTRK2\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: BDNF\/NT-3 Growth Factors Receptor; GP145-TrkB; Trk-B; Neurotrophic Tyrosine Kinase Receptor Type 2; TrkB Tyrosine Kinase; Tropomyosin-Related Kinase B; NTRK2; TRKB\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Neuroscience; Cancer; metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: ELISA\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q16620\u003c\/p\u003e\n\n\u003cp\u003eAccession: Q16620\u003c\/p\u003e\n\n\u003cp\u003eBackground: The TRK Family of Tyrosine Kinase Receptor consists of 3 members: TrkA, TrkB and TrkC. The three TRK family proteins have different ligand specificities. They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4\/5. TRKA binds NGF, TRKB binds BDNF and NT-3, TRKC binds NT-4\/5. At the protein sequence level, human and rat TRKB have greater than 90% sequence identity and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low levels.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Immobilized Human NT-3(Cat: PKSH032803) at 2μg\/ml(100 μl\/well) can bind Human TrkB-His. The ED50 of Human TrkB-His is 3. 777ug\/ml.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Cys32-His430\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 45.25 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60-105 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43107265708211,"sku":"PKSH033579-50","price":207.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_712721c2-8ca0-45b1-b778-2fcf9dfaf6a3.png?v=1709382186","url":"https:\/\/afsbio.com\/products\/recombinant-human-trkb-ntrk2-protein-his-tagactive-pksh033579","provider":"AFSBio Inc.","version":"1.0","type":"link"}