{"product_id":"recombinant-human-tryptase-β-2-tpsb2-protein-his-tag-pksh033154","title":"Recombinant Human Tryptase β-2\/TPSB2 Protein (His Tag) - PKSH033154","description":"\u003cp\u003eRecombinant Human Tryptase β-2\/TPSB2 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033154-10, PKSH033154-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Tryptase β-2; TPSB2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Tryptase Beta-2; Tryptase-2; Tryptase II; TPSB2; TPS2\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P20231\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P20231\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala19-Pro275\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 29.6 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 30 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43149118963891,"sku":"PKSH033154-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43149118996659,"sku":"PKSH033154-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_796e010f-b185-495a-ad0e-9fe41298082e.png?v=1710340982","url":"https:\/\/afsbio.com\/products\/recombinant-human-tryptase-%ce%b2-2-tpsb2-protein-his-tag-pksh033154","provider":"AFSBio Inc.","version":"1.0","type":"link"}