{"product_id":"recombinant-human-u2-small-nuclear-rna-auxiliary-factor-1-his-tagged-u2af1-580h","title":"Recombinant Human U2 small nuclear RNA auxiliary factor 1, His-tagged - U2AF1-580H","description":"\u003cp\u003eU2AF1, 1-240aa, Human, His tag, \u003cem\u003eE. coli\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003eSizes: 100ug, 500ug\u003c\/p\u003e\n\u003cp\u003eCatalogue Numbers: U2AF1-580H-100, U2AF1-580H-500\u003c\/p\u003e\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\u003cp\u003eSource: E.coli\u003c\/p\u003e\n\u003cp\u003eTag: His\u003c\/p\u003e\n\u003cp\u003eProtein Length: 1-240 a.a.\u003c\/p\u003e\n\u003cp\u003eDescription: U2AF1 belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This protein is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Recombinant human U2AF1 protein, fused to His-tag at N-terminus, was expressed in E. coli.\u003c\/p\u003e\n\u003cp\u003eForm: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol\u003c\/p\u003e\n\u003cp\u003eMolecular Mass: 30.3 kDa (263aa)\u003c\/p\u003e\n\u003cp\u003eAA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAEYLAS IFGTEKDKVN CSFYFKIGAC RHGDRCSRLH NKPTFSQTIL IQNIYRNPQN SAQTADGSHC AVSDVEMQEH YDEFFEEVFT EMEEKYGEVE EMNVCDNLGD HLVGNVYVKF RREEDAEKAV IDLNNRWFNG QPIHAELSPV TDFREACCRQ YEMGECTRGG FCNFMHLKPI SRELRRELYG RRRKKHRSRS RSRERRSRSR DRGRGGGGGG GGGGGGRERD RRRSRDRERS GRF\u003c\/p\u003e\n\u003cp\u003ePurity: \u0026gt;90% by SDS - PAGE\u003c\/p\u003e\n\u003cp\u003eStorage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.\u003c\/p\u003e\n\u003cp\u003eConcentration: 1 mg\/ml (determined by Bradford assay)\u003c\/p\u003e\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Creative BioMart","offers":[{"title":"100ug","offer_id":45483400626355,"sku":"U2AF1-580H-100","price":1328.11,"currency_code":"CAD","in_stock":true},{"title":"500ug","offer_id":45483400659123,"sku":"U2AF1-580H-500","price":2748.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Screenshot_2023-11-21_195502_10752e1e-c404-4a78-8a42-6390b4ea3141.png?v=1713291656","url":"https:\/\/afsbio.com\/products\/recombinant-human-u2-small-nuclear-rna-auxiliary-factor-1-his-tagged-u2af1-580h","provider":"AFSBio Inc.","version":"1.0","type":"link"}