{"product_id":"recombinant-human-vapb-protein-his-tagactive-pksh033405","title":"Recombinant Human VAPB Protein (His Tag)(Active) - PKSH033405","description":"\u003cp\u003eRecombinant Human VAPB Protein (His Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033405-10, PKSH033405-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: VAPB\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Vesicle-associated membrane protein-associated protein B\/C; VAMP-B\/VAMP-C; VAMP-associated protein B\/C; VAP-B\/VAP-C\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eApplication: ELISA\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O95292\u003c\/p\u003e\n\n\u003cp\u003eAccession: O95292-1\u003c\/p\u003e\n\n\u003cp\u003eBackground: vesicle-associated membrane protein-associated protein B\/C (VAPB) is presents in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane. It can form homodimer; and heterodimer with VAPA. It also interacts with VAMP1; VAMP2; HCV NS5A; NS5B; ZFYVE27 and RMDN3. VAPB participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1\/IRE1 activity. It is involved in cellular calcium homeostasis regulation.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Immobilized Human EphB2-Fc(Cat: PKSH032012) at 1μg\/ml(100 μl\/well) can bind Human VAMPB-His. The ED50 of Human VAMPB-His is 5. 179ug\/ml.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala2-Pro132\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 16.0 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 16 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43114028400819,"sku":"PKSH033405-10","price":163.8,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43114028433587,"sku":"PKSH033405-50","price":415.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_8bb6ae46-2e6c-494e-8bce-fbe00059bc5e.png?v=1709550470","url":"https:\/\/afsbio.com\/products\/recombinant-human-vapb-protein-his-tagactive-pksh033405","provider":"AFSBio Inc.","version":"1.0","type":"link"}