{"product_id":"recombinant-human-vegf-b-vegfb-protein-fc-tag-pksh033474","title":"Recombinant Human VEGF-B\/VEGFB Protein (Fc Tag) - PKSH033474","description":"\u003cp\u003eRecombinant Human VEGF-B\/VEGFB Protein (Fc Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033474-10, PKSH033474-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: VEGF-B; VEGFB\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; Cardiovascular; Neuroscience; Cancer;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-Fc\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P49765\u003c\/p\u003e\n\n\u003cp\u003eAccession: P49765\u003c\/p\u003e\n\n\u003cp\u003eBackground: VEGFB, as known as VRF, is a member of the VEGF family of growth factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane receptor for semaphorins\/collapsins, ligands involved in neuron guidance.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Pro22-Ala207\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 45.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 40\u0026amp;60 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113960439987,"sku":"PKSH033474-10","price":180.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113960472755,"sku":"PKSH033474-50","price":525.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_eb892286-ddb3-4f90-a0ff-12c3074711be.png?v=1709549213","url":"https:\/\/afsbio.com\/products\/recombinant-human-vegf-b-vegfb-protein-fc-tag-pksh033474","provider":"AFSBio Inc.","version":"1.0","type":"link"}