{"product_id":"recombinant-human-wnt3a-protein-his-tag-pdeh100436","title":"Recombinant Human WNT3A protein (His tag) - PDEH100436","description":"\u003cp\u003eRecombinant Human WNT3A protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDEH100436-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: WNT3A\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Protein Wnt-3a; WNT3A\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P56704\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Developmental Biology; \u003cbr\u003e\nNeuroscience; Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P56704\u003c\/p\u003e\n\n\u003cp\u003eBackground: Wnt-3a is one of 19 vertebrate members of the Wingless-type MMTV integration site (Wnt) family of highly conserved cysteine-rich secreted glycoproteins important for normal developmental processes. Wnts bind to the cell surface Frizzled family receptors in conjunction with low-density lipoprotein receptor-related protein family receptors (LRP5 or 6) resulting in the stabilization of intracellular beta -catenin levels. As intracellular beta -catenin levels rise, beta -catenin binds to TCF\/LEF transcription factors leading to expression of Wnt target genes.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ser19-Lys325\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 33.66 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 38 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43083563008179,"sku":"PDEH100436-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_010c6b94-166c-4635-9717-ac75cb7cf9f0.png?v=1708944750","url":"https:\/\/afsbio.com\/products\/recombinant-human-wnt3a-protein-his-tag-pdeh100436","provider":"AFSBio Inc.","version":"1.0","type":"link"}