{"product_id":"recombinant-human-xpnpep2-protein-his-tag-pksh033349","title":"Recombinant Human XPNPEP2 Protein (His Tag) - PKSH033349","description":"\u003cp\u003eRecombinant Human XPNPEP2 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033349-10, PKSH033349-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: XPNPEP2\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: Xaa-Pro Aminopeptidase 2; Aminoacylproline Aminopeptidase; Membrane-Bound Aminopeptidase P; Membrane-Bound APP; Membrane-Bound AmP; mAmP; X-Pro Aminopeptidase 2; XPNPEP2\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Signal Transduction; Cell biology; Cancer; metabolism;\u003c\/p\u003e \n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O43895\u003c\/p\u003e\n\n\u003cp\u003eAccession: O43895\u003c\/p\u003e\n\n\u003cp\u003eBackground: Xaa-Pro aminopeptidase 2 (XPNPEP2) belongs to the peptidase M24B family of metalloproteases. Human XPNPEP2 is widely expressed in various tissues; such as kidney; lung; heart; placenta; liver; small intestine and colon. However; it doesn’t express in brain; skeletal muscle; pancreas; spleen; thymus; prostate; testis and ovary. XPNPEP2 is a Homotrimer which binds 2 manganese ions per subunit. The metalloprotease XPNPEP2 may play a role in the inflammatory process and other reactions produced in response to injury or infection and the metabolism of the vasodilator bradykinin.\u003c\/p\u003e\n\n\u003cp\u003eSequence: His22-Ala650\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 71.6 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 78 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113951887539,"sku":"PKSH033349-10","price":312.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113951920307,"sku":"PKSH033349-50","price":830.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_5f8a394f-6dba-4e60-9163-44e8e5b08174.png?v=1709549112","url":"https:\/\/afsbio.com\/products\/recombinant-human-xpnpep2-protein-his-tag-pksh033349","provider":"AFSBio Inc.","version":"1.0","type":"link"}