{"product_id":"recombinant-human-zic3-protein-his-tag-pdeh100321","title":"Recombinant Human Zic3 protein (His tag) - PDEH100321","description":"\u003cp\u003eRecombinant Human Zic3 protein (His tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDEH100321-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Zic3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Zinc finger protein ZIC 3; ZIC3; Zinc finger protein 203; Zinc finger protein of the cerebellum 3\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O60481\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Developmental Biology; Epigenetics and Nuclear signaling; Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His \u0026amp; C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: O60481\u003c\/p\u003e\n\n\u003cp\u003eBackground: ZIC3 (zinc-finger protein of the cerebellum 3) is a 50 kDa (predicted) member of the GLI C2H2-type Zn-finger protein family. It is expressed in cerebellum, and apparently plays a key role in left-right body axis formation. Human ZIC3 is 467 amino acids (aa) in length. It contains N-terminal poly-Ala (aa 46-55) and poly-His (aa 87-97) segments, followed by five C2H2-type Zn-fingers (aa 253-410). Within the zinc finger region, there is an overlapping NES (aa 290-349) and two NLS's (aa 367-382 and 403-410). ZIC3 reportedly binds to GLI-3.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Val467\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 51.26 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 52 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"100μg","offer_id":43083546132659,"sku":"PDEH100321-100","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_97a5afc2-3c7c-4be7-bf32-f9973a5b89f6.png?v=1708944456","url":"https:\/\/afsbio.com\/products\/recombinant-human-zic3-protein-his-tag-pdeh100321","provider":"AFSBio Inc.","version":"1.0","type":"link"}