{"product_id":"recombinant-human-zwint-protein-his-tag-pksh033243","title":"Recombinant Human ZWINT Protein (His Tag) - PKSH033243","description":"\u003cp\u003eRecombinant Human ZWINT Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSH033243-10, PKSH033243-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ZWINT\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: ZW10 Interactor; ZW10-Interacting Protein 1; Zwint-1; ZWINT\u003c\/p\u003e\n\n\u003cp\u003eResearch Area: Cell biology; epigenetics and nuclear signal\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Human\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-6His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: O95229\u003c\/p\u003e\n\n\u003cp\u003eAccession: O95229\u003c\/p\u003e\n\n\u003cp\u003eBackground: ZW10 Interactor is localized to the kinetochores from late Prophase to Anaphase and has a uniform distribution in the cytoplasm of Interphase cells. ZWINT interacts ZW10, MIS12 and NDC80 subunit of the NDC80 complex specifically during mitosis. ZWINT is a part of the MIS12 complex which is required for kinetochore formation and spindle checkpoint activity. In addition, ZWINT is required to target ZW10 to the kinetochore at prometaphase.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met 1-Pro277\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 33.4 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 36 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43113936158899,"sku":"PKSH033243-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43113936191667,"sku":"PKSH033243-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_0b0d7dfe-917d-44dd-a1e3-6f955ab2a1ff.png?v=1709548904","url":"https:\/\/afsbio.com\/products\/recombinant-human-zwint-protein-his-tag-pksh033243","provider":"AFSBio Inc.","version":"1.0","type":"link"}