{"product_id":"recombinant-ifn-γ-human-bk0080","title":"Recombinant IFN-γ, Human - BK0080","description":"\u003cp\u003eRecombinant IFN-γ, Human\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0080-10, BK0080-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 17kDa, observed by reducing SDS‐PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% as analyzed by reducing SDS‐PAGE.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50\u0026lt;0.05ng\/ml, measured by cytotoxicity assay using HT‐29 cells.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MQDPYVKEA ENLKKYFNAG HSDVADNGTL FLGILKNWKE ESDRKIMQSQ IVSFYFKLFK NFKDDQSIQK SVETIKEDMN VKFFNSNKKK RDDFEKLTNY SVTDLNVQRK AIHELIQVMA ELSPAAKTGK RKRSQMLFRG RRASQ\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt;1 EU\/μg, determined by LAL\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant human Interferon gamma (rhIFN‐γ) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhIFN-γ should be stable up to 1 week at 4°C or up to 2 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Human Interferon gamma (hIFN-γ) is amacrophage‐activating factor and the lone member of Interferon type II.The active form of IFN-γ is an antiparallel dimer that interacts with the receptor IFN-γR1 and sets off IFN-γ\/JAK\/STAT pathway. IFN-γ signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. While IFN-γ–induced inflammatory cascade summons a variety of immune‐related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN-γ is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers.Recombinant human Interferon gamma (rhIFN-γ) produced in E.coli is a non‐glycosylated polypeptide chain of 144 amino acids. A fully biologically active molecule, rhIFN-γ has a molecular mass of 17 kDa analyzed by reducing SDS‐PAGE and is obtained by proprietary refolding and chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882240839859,"sku":"BK0080-10","price":217.41,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":42882240872627,"sku":"BK0080-100","price":691.77,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_bbe33a26-c520-4cb4-a778-e2ae3e57a5b4.jpg?v=1702049873","url":"https:\/\/afsbio.com\/products\/recombinant-ifn-%ce%b3-human-bk0080","provider":"AFSBio Inc.","version":"1.0","type":"link"}