{"product_id":"recombinant-ifn-γ-rat-bk0082","title":"Recombinant IFN-γ, Rat - BK0082","description":"\u003cp\u003eRecombinant IFN-γ, Rat\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0082-10, BK0082-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 15.5 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% as analyzed by SDS-PAGE and HPLC.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt;0.5 ng\/ml, measured by cytotoxicity assay using WEHI-279 cells, corresponding to a specific activity of \u0026gt;2×10ˆ6 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: GT LIESLESLKN YFNSSSMDAM EGKSLLLDIW RNWQKDGNTK ILESQIISFY LRLFEVLKDN QAISNNISVI ESHLITNFFS NSKAKKDAFM SIAKFEVNNP QIQHKAVNEL IRVIHQLSPE SSLRKRKRSR C\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant Rat IFN-γ remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, recombinant Rat IFN-γ should be stable up to 1 week at 4°C or up to 2 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Interferon gamma (IFN-γ), also known as Type II interferon,is a cytokine produced primarily by T-lymphocytes and natural killer cells. The active form of IFN-γ is an antiparallel dimer that interacts with the receptor IFN-γR1 and activates the IFN-γ\/JAK\/STAT pathway. IFN-γ signaling promotesbiological functions primarily related to antiviral and antibacterial defense, apoptosis, inflammation, and regulation of innate and acquired immune responses. While IFN-γ–induced inflammatory cascades summon a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN-γ is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers.Recombinant Rat Interferon gamma (IFN-γ) produced in E.coli is a single non-glycosylated polypeptide chain containing 134 amino acids. A fully biologically active molecule, rrIFN-γ has a molecular mass of 15.5 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882240970931,"sku":"BK0082-10","price":217.41,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882241003699,"sku":"BK0082-50","price":375.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_cba19aca-5d4f-4c55-898a-cff370b44ec5.jpg?v=1702049877","url":"https:\/\/afsbio.com\/products\/recombinant-ifn-%ce%b3-rat-bk0082","provider":"AFSBio Inc.","version":"1.0","type":"link"}