{"product_id":"recombinant-il-11-mouse-hek293-expre-ssed-bk0311","title":"Recombinant IL-11, Mouse (HEK293-expressed) - BK0311","description":"\u003cp\u003eRecombinant IL-11, Mouse (HEK293-expressed)\u003c\/p\u003e\n\u003cp\u003eCatalogue Numbers: BK0311-10, BK0311-50\u003c\/p\u003e\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\u003cp\u003eSource: HEK 293\u003c\/p\u003e\n\u003cp\u003eMolecular Weight: ~21 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\u003cp\u003ePurity: \u0026gt; 95% as analyzed by SDS-PAGE and HPLC.\u003c\/p\u003e\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 3 ng\/ml, measured in a cell proliferation assay using T11 cells.\u003c\/p\u003e\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\u003cp\u003eAA Sequence: GPPAGSPRVSSDPRADLDSAVLLTRSLLADTRQLAAQMRDKFPADGDHSLDSLPTLAMSAGTLGSLQLPGVLTRLRVDLM\u003cbr\u003e SYLRHVQWLRRAGGPSLKTLEPELGALQARLERLLRRLQLLMSRLALPQAAPDQPVIPLGPPASAWGSIRAAHAILGGLH\u003cbr\u003e LTLDWAVRGLLLLKTRL\u003c\/p\u003e\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\u003cp\u003eStorage: Lyophilized recombinant Murine Interleukin-11 (IL-11) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Murine Interleukin-11 (IL-11) should be stable up to 1 week at 4°C or up to 2 months at -20°C.\u003c\/p\u003e\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\u003cp\u003eDescription: Interleukin-11 (IL-11) is a pleiotropic cytokine that was originally detected in the conditioned medium of an IL-1α-stimulated primate bone marrow stromal cell line (PU-34) as a mitogen for the IL-6-responsive mouse plasmacytoma cell line T11. IL-11 contains no cysteine residues or potential glycosylation sites. IL-11 has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL-11 overlap those for IL-6. In vitro, IL-11 can synergize with IL-3, IL-4 and SCF to shorten the G0 period of early hematopoietic progenitors. IL-11 also enhances the IL-3-dependent megakaryocyte colony formation. IL-11 has been found to stimulate the T cell dependent development of specific immunoglobulin-secreting B cell.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882262302899,"sku":"BK0311-10","price":0.0,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882262335667,"sku":"BK0311-50","price":0.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a20ddb71-2926-490c-950c-b8340459b226.jpg?v=1702050284","url":"https:\/\/afsbio.com\/products\/recombinant-il-11-mouse-hek293-expre-ssed-bk0311","provider":"AFSBio Inc.","version":"1.0","type":"link"}