{"product_id":"recombinant-il-19-mouse-bk0093","title":"Recombinant IL-19, Mouse - BK0093","description":"\u003cp\u003eRecombinant IL-19, Mouse\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0093-10, BK0093-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 17.7 kDa, observed by non-reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% by SDS-PAGE analysis.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 50 ng\/mL, measured by a cell proliferation assay using MCF-7 cells, corresponding to a specific activity of \u0026gt; 2× 10ˆ4 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against 50mM acetic acid.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MLRRCLISV DMRLIEKSFH EIKRAMQTKD TFKNVTILSL ENLRSIKPGD VCCMTNNLLT FYRDRVFQDH QERSLEVLRR ISSIANSFLC VQKSLERCQV HRQCNCSQEA TNATRIIHDN YNQLEVSSAA LKSLGELNIL LAWIDRNHLE TPAA\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in 50 mM acetic acid at 50 μg\/mL.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant mouse Interleukin-19 (rmIL-19) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmIL-19 remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Interleukin-19 (IL-19) is a cytokine belonging to the interleukin family. Structurally, IL-19 is grouped into the IL-10 sub-family, which also includes IL-20, IL-22, IL-24, and IL-26. In contrast to IL-10, which exists as a homodimer, IL-19 is stable and active as a monomer in vivo. IL-19 functions through the receptor complex composed of IL-20 Receptor α and IL-20 Receptor β, which is also utilized by IL-20 and IL-24. IL-19 is produced by active monocytes and stimulated synergistically by IL-17 and IL-13. The functions of IL-19 are to promote the development and function of Th2 cells and to enhance the production of Th2 cytokines. IL-19 is implicated in aging, vascular disease, Type I diabetes, and rheumatoid arthritis. Recombinant mouse Interleukin-19 (rmIL-19) produced in E.coli is a single non-glycosylated polypeptide chain containing of153 amino acids. A fully biologically active molecule, rmIL-19 has a molecular mass of 17.7 kDa analyzed by non-reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882241822899,"sku":"BK0093-10","price":375.54,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882241855667,"sku":"BK0093-50","price":1317.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_972c6c6a-fa7e-47b9-a562-61c464dc2091.jpg?v=1702049903","url":"https:\/\/afsbio.com\/products\/recombinant-il-19-mouse-bk0093","provider":"AFSBio Inc.","version":"1.0","type":"link"}