{"product_id":"recombinant-il-22-mouse-bk0101","title":"Recombinant IL-22, Mouse - BK0101","description":"\u003cp\u003eRecombinant IL-22, Mouse\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0101-10, BK0101-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 16.8 kDa, observed by reducing SDS-PAGE\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 98% as analyzed by SDS-PAGE\u0026amp; HPLC.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 0.5 ng\/ml. Measured by its ability to induce IL-10 secretion in COLO 205 (human colon carcinoma cells).\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MLPVNTRCKL EVSNFQQPYI VNRTFMLAKE ASLADNNTDV RLIGEKLFRG\u003cbr\u003e\n VSAKDQCYLM K\u003cbr\u003e\n QVLNFTLED VLLPQSDRFQ PYMQEVVPFL TKLSNQLSSC\u003cbr\u003e\n HISGDDQNIQ KNVRRLKEt V K\u003cbr\u003e\n KLGESGEIK AIGELDLLFM SLRNACV\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant Mouse IL-22 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Mouse IL-22 should be stable up to 1 week at 4°C or up to 3 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Interleukin-22 (IL-22) is a member of a group of cytokines called the IL-10 family which include IL-10,IL-19, IL-20, IL-24, and IL-26. IL-22 shares use of the IL-10R2 in cell signaling with other members of this family IL-22 signals through a receptor system consisting of IL-10R-ß\/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. IL-22 is produced by activated DCs and T cells and initiates an innate immune response against bacterial pathogens especially in epithelial cells such as those in the respiratory tract and gut. IL-22 along with IL-17 is rapidly produced by splenic LTi-like cells and can also be produced by Th17 cells, which plays a likely role in the coordinated response of both adaptive and innate immune systems.Recombinant MouseIL-22 produced in E.coli is a single non-glycosylated polypeptide chain containing 147 amino acids. A fully biologically active molecule, rmIL-22 has a molecular mass of 16.8 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882242511027,"sku":"BK0101-10","price":256.94,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882242543795,"sku":"BK0101-50","price":813.32,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_e1ec267b-eab6-405a-a249-18f121fb1cad.jpg?v=1702049918","url":"https:\/\/afsbio.com\/products\/recombinant-il-22-mouse-bk0101","provider":"AFSBio Inc.","version":"1.0","type":"link"}