{"product_id":"recombinant-il-5-human-bk0106","title":"Recombinant IL-5, Human - BK0106","description":"\u003cp\u003eRecombinant IL-5, Human\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0106-10, BK0106-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 26.5 kDa, observed by non-reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 1.0 ng\/ml, measured by a cell proliferation assay using TF-1 Cells, corresponding to a specific activity of \u0026gt; 1.0× 10ˆ6 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against 25mM Tris, pH8.0.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MIPTEIPTS ALVKETLALL STHRTLLIAN ETLRIPVPVH KNHQLCTEEI FQGIGTLESQ t VQGGt VERL FKNLSLIKKY IDGQKKKCGE ERRRVNQFLD YLQEFLGVMN TEWIIES\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant Human Interleukin-5 (rhIL-5) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhIL-5 should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.Recombinant Human Interleukin-5 (rhIL-5) produced in E.coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 116 amino acids each. A fully biologically active molecule, rhIL-5 has a molecular mass of 26.5 kDa analyzed by non-reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882243100851,"sku":"BK0106-10","price":256.94,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882243133619,"sku":"BK0106-50","price":691.77,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_4e4d7a8a-c812-4839-a710-dc3ea97c03d2.jpg?v=1702049927","url":"https:\/\/afsbio.com\/products\/recombinant-il-5-human-bk0106","provider":"AFSBio Inc.","version":"1.0","type":"link"}