{"product_id":"recombinant-il-5-rat-bk0108","title":"Recombinant IL-5, Rat - BK0108","description":"\u003cp\u003eRecombinant IL-5, Rat\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0108-10, BK0108-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 26.0 kDa, observed by non-reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% by SDS-PAGE analysis.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 0.4 ng\/mL, measured by a cell proliferation assay using TF-1 Cells, corresponding to a specific activity of \u0026gt; 2.5× 10ˆ6 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against 20mM Tris, pH8.5.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MEIPMSt VV KETLIQLSTH RALLTSNETM RLPVPTHKNH QLCIGEIFQG LDILKNQt VR GGt VEILFQN LSLIKKYIDG QKEKCGEERR KTRHFLDYLQ EFLGVMSTEW AMEV\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O at 100 μg\/mL.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant rat Interleukin-5 (rrIL-5) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rrIL-5 should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.Recombinant rat Interleukin-5 (rrIL-5) produced in E.coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 113 amino acids each. A fully biologically active molecule, rrIL-5 has a molecular mass of 26.0 kDa analyzed by non-reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882243297459,"sku":"BK0108-10","price":256.94,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882243330227,"sku":"BK0108-50","price":813.32,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_ca9d5b06-5d5e-44de-9802-83ff9c7db2d7.jpg?v=1702049930","url":"https:\/\/afsbio.com\/products\/recombinant-il-5-rat-bk0108","provider":"AFSBio Inc.","version":"1.0","type":"link"}