{"product_id":"recombinant-impdh2-monoclonal-antibody-e-ab-81572","title":"Recombinant IMPDH2 Monoclonal Antibody - E-AB-81572","description":"\u003cp\u003eRecombinant IMPDH2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-81572-50, E-AB-81572-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IMPDH2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: IMDH2; IMP (inosine monophosphate) dehydrogenase 2; IMP dehydrogenase 2; IMP oxireductase 2; IMPD 2; IMPD2; IMPDH 2; IMPDH II; IMPDH-II; Impdh2; Inosine 5' monophosphate dehydrogenase 2; Inosine 5' phosphate dehydrogenase 2; Inosine monophosphate dehydrogenase type II; Inosine-5''-monophosphate dehydrogenase 2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC-P\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Rabbit Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone No.: R06-1B8\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P12268\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 300 μg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human IMPDH2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1000-1:2000 IHC 1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 56kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 56kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μL","offer_id":43149039108275,"sku":"E-AB-81572-50","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":43149039141043,"sku":"E-AB-81572-100","price":364.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_5d0ca1bc-9ee5-425f-992c-a90ca13177a2.png?v=1710338928","url":"https:\/\/afsbio.com\/products\/recombinant-impdh2-monoclonal-antibody-e-ab-81572","provider":"AFSBio Inc.","version":"1.0","type":"link"}