{"product_id":"recombinant-ip-10-cxcl10-human-bk0112","title":"Recombinant IP-10\/CXCL10, Human - BK0112","description":"\u003cp\u003eRecombinant IP-10\/CXCL10, Human\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0112-10, BK0112-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 8.6 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 0.2μg\/ml, measured by a cell proliferation assay of HUVEC cells in the presence of 2.5ng\/ml h-VEGF, corresponding to a specific activity of \u0026gt; 5.0× 10ˆ3 IU\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against 50mM Tris, pH8.0.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MVPLSRt VR CTCISISNQP VNPRSLEKLE IIPASQFCPR VEIIATMKKK GEKRCLNPES KAIKNLLKAV SKEMSKRSP\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant human IP-10\/CXCL10 (rhIP-10) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhIP-10 should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: IP-10\/CXCL10 also known as CXCL10, is originally identified as an IFN-γ-inducible gene in monocytes, fibroblasts and endothelial cells. It has since been shown that IP-10 mRNA is also induced by LPS, IL-1β, TNF-α, IL-12 and viruses. Additional cell types that have been shown to express IP-10 include activated T-lymphocytes, splenocytes, keratinocytes, osteoblasts, astrocytes, and smooth muscle cells. IP-10 is also expressed in psoriatic and lepromatous lesions of skin. The mouse homologue of human IP-10, Crg-2, has been cloned and shown to share approximately 67% amino acid sequence identity with human IP-10.Recombinant human IP-10\/CXCL10 (rhIP-10) produced in E. coli is a single non-glycosylated polypeptide chain containing 78 amino acids. A fully biologically active molecule, rhIP-10 has a molecular mass of 8.6kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882243625139,"sku":"BK0112-10","price":217.41,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882243657907,"sku":"BK0112-50","price":444.71,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_03e11043-412b-44b9-878c-c0670fd3f056.jpg?v=1702049937","url":"https:\/\/afsbio.com\/products\/recombinant-ip-10-cxcl10-human-bk0112","provider":"AFSBio Inc.","version":"1.0","type":"link"}