{"product_id":"recombinant-k-pneumoniae-neo-ept008","title":"Recombinant K. pneumoniae NEO - EPT008","description":"\u003cp\u003eRecombinant K. pneumoniae NEO\u003c\/p\u003e\n\n\u003cp\u003eSize: 50ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: EPT008-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Aminoglycoside 3'-phosphotransferase (APH (3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydroxyl of a variety of aminoglycosides including kanamycins, neomycins, paromomycins, neamine, ribostamycin, geneticin, and paromamine. These phosphorylated aminoglycosides fail to bind to their respective ribosomal binding sites with high affinity; hence resistance is conferred to the drugs that are phosphorylated. APH (3') is primarily found in certain species of gram-positive bacteria.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Aminoglycoside 3'-phosphotransferase; APH (3')-II; APH (3')II; Kanamycin kinase type II; Neomycin-kanamycin phosphotransferase type II; neo\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Klebsiella Pneumoniae Aminoglycoside 3'-phosphotransferase is produced by our E.coli expression system and the target gene encoding Met1-Phe264 is expressed.\u003c\/p\u003e\n\n\u003cp\u003eAccession: P00552\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 29 KDa\u003c\/p\u003e\n\n\u003cp\u003eApparent Molecular Weight: 26-30 KDa, reducing conditions\u003c\/p\u003e\n\n\u003cp\u003eStorage Condition: Lyophilized protein should be stored at \u0026lt; -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20°C for 3 months.\u003c\/p\u003e\n\n\u003cp\u003ePurity: Greater than 95% as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 0.1 ng\/µg (1 EU\/µg) as determined by LAL test.\u003c\/p\u003e\n\n\u003cp\u003eDelivery Condition: The product is shipped on dry ice\/polar packs. Upon receipt, store it immediately at the temperature listed below.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.\u003c\/p\u003e \n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"Default Title","offer_id":43211011031219,"sku":"EPT008-50","price":824.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_360ff37b-1bfb-41e3-91e0-655c46af044e.png?v=1767117520","url":"https:\/\/afsbio.com\/products\/recombinant-k-pneumoniae-neo-ept008","provider":"AFSBio Inc.","version":"1.0","type":"link"}