{"product_id":"recombinant-lix-cxcl574aa-mouse-bk0262","title":"Recombinant LIX\/CXCL5(74aa), Mouse - BK0262","description":"\u003cp\u003eRecombinant LIX\/CXCL5(74aa), Mouse\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0262-10, BK0262-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: CHO\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 8 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 98% as analyzed by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: The EC50 value of mouse LIX\/CXCL5 (74aa) on Caˆ2+ mobilization assay in CHO-K1\/Gα15\/mCXCR2 cells (human Gα15 and mouse CXCR2 stably expressed in CHO-K1 cells) is less than 200 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: VIAATELRCVCLt VTPKINPKLIANLEVIPAGPQCPt VEVIAKLKNQKEVCLDPEA\u003cbr\u003e\n PVIKKIIQKILGSDKKKA\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant mouse LIX\/CXCL5 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution,mouse LIX\/CXCL5 should be stable up to 1 week at 4°C or up to 2 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Mouse LIX (C-X-C motif chemokine 5) is a small cytokine belonging to the CXC chemokine family that is cleaved into the following 2 chains [GCP-2(1-78) and GCP-2(9-78)]. Mouse LIX plays a role in reducing sensitivity to sunburn pain in some subjects, and is a potential target which could be used to understand more about pain in other inflammatory conditions. It is most closely related to two highly homologous human neutrophil chemoattractants GCP-2 and ENA-78. The first 78 amino acid residues within the predicted mature mouse LIX shares approximately 61% and 55% amino acid identity with human GCP-2 and ENA-78. This chemokine stimulates the chemotaxis of neutrophils possessing angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2.Recombinant mouse LIX\/CXCL5 (74aa) produced in CHO cells is a single polypeptide chain containing 74 amino acids. rmLIX\/CXCL5(74aa) has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882257682611,"sku":"BK0262-10","price":217.41,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882257715379,"sku":"BK0262-50","price":691.77,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_4cce149b-6002-4f2f-b0cc-ea15dd69df35.jpg?v=1702050181","url":"https:\/\/afsbio.com\/products\/recombinant-lix-cxcl574aa-mouse-bk0262","provider":"AFSBio Inc.","version":"1.0","type":"link"}