{"product_id":"recombinant-lr3-igf-ireceptorgrade-human-bk0123","title":"Recombinant LR3-IGF-I(ReceptorGrade), Human - BK0123","description":"\u003cp\u003eRecombinant LR3-IGF-I(ReceptorGrade), Human\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0123-100, BK0123-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100μg, 10μg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 9.1±0.9 KDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 ＜10 ng\/ml, measured by the dose-dependantproliferation of CHO cells, corresponding to a specific activity of \u0026gt;1.0× 10ˆ5 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after dissolved in 48%acetonitrile and 0.1% TFA\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK\u003cbr\u003e\n PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA\u003cbr\u003e\n KSA\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: ＜1 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in 10mM HCl at 1mg\/ml. Use a 0.22 μm membrane for filter Sterilization.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant human Long R3Insulin-like Growth Factor-1 (rhLR3IGF-1) remains stable up to 6 months at -80°C from date of receipt. Stock solution of peptide can be stored at least 3 months at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: IGF-1 is a well-characterized basic peptide secreted by the liver that circulates in the blood. It has growth-regulating, insulin-like, mitogenic activities. IGF-1 is a growth factor that has a major, but not absolute, dependence on somatotropin. It is believed to be mainly active in adults in contrast to IGF-2, which is also a major fetal growth factor. Human Long R3 Insulin-like Growth Factor-1 (rhLR3IGF-1) contains an 83 amino acid analog of human IGF-I. Compared to the complete human IGF-I sequence, an addition of the rhLR3IGF-1 includes the substitution of an Arg for the Glu at position 3 (hence R3)and a13 amino acid extension peptide at the N-terminus. An enhanced potency is due to the markedly decreased binding of human Long-R3-IGF-I to IGF binding proteins which normally inhibit the biological actions of IGFs. RhLR3IGF-1 is properly folded under oxidizing conditions and then purified by proprietary chromatographic techniques at GenScript.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"100μg","offer_id":42882244313267,"sku":"BK0123-100","price":217.41,"currency_code":"CAD","in_stock":true},{"title":"10μg","offer_id":42882244346035,"sku":"BK0123-10","price":217.41,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_4a4c35c1-7437-4214-aec6-b36d0619586f.jpg?v=1702049953","url":"https:\/\/afsbio.com\/products\/recombinant-lr3-igf-ireceptorgrade-human-bk0123","provider":"AFSBio Inc.","version":"1.0","type":"link"}