{"product_id":"recombinant-mers-cov-nucleoprotein-np-protein-his-tag-pksv030235","title":"Recombinant MERS-CoV Nucleoprotein \/ NP protein (His Tag) - PKSV030235","description":"\u003cp\u003eRecombinant MERS-CoV Nucleoprotein \/ NP protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSize: 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: PKSV030235-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Nucleoprotein; NP\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: coronavirus NP Protein; MERS-CoV; coronavirus Nucleocapsid Protein; MERS-CoV; coronavirus Nucleoprotein Protein; MERS-CoV; cov np Protein; MERS-CoV; ncov NP Protein; MERS-CoV; novel coronavirus Nucleoprotein Protein; MERS-CoV; NP Protein; MERS-CoV; Nucleocapsid Protein; MERS-CoV; Nucleoprotein Protein; MERS-CoV\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: MERS-CoV\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: Baculovirus-Insect Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: AFS88943.1\u003c\/p\u003e\n\n\u003cp\u003eBackground: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Met1-Asp413\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 46.51 kDa.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"Default Title","offer_id":43107301589171,"sku":"PKSV030235-100","price":1547.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b3d0e539-932e-43b9-a870-6ca5ce586add.png?v=1709382523","url":"https:\/\/afsbio.com\/products\/recombinant-mers-cov-nucleoprotein-np-protein-his-tag-pksv030235","provider":"AFSBio Inc.","version":"1.0","type":"link"}