{"product_id":"recombinant-mers-cov-spike-s1-protein-rp01303","title":"Recombinant MERS-CoV Spike S1 Protein - RP01303","description":"\u003cp\u003eRecombinant MERS-CoV Spike S1 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: RP01303-10, RP01303-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant MERS-CoV Spike S1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Tyr18-Glu725) of mers-cov Spike S1 (Accession #YP_009047204.1) fused with a mFc tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: MERS-CoV Spike RBD\u003c\/p\u003e\n\n\u003cp\u003eSWISS: K9N5Q8\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 14254594\u003c\/p\u003e\n\n\u003cp\u003eSpecies: MERS-CoV\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD26 (Catalog: RP01300LQ) at 2μg\/mL (100μL\/well) can bind MERS-CoV Spike S1 with a linear range of 0.5-420.21ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-mFc\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: YVDVGPDSVKSACIEVDIQQTFFDKTWPRPIDVSKADGIIYPQGRTYSNITITYQGLFPYQGDHGDMYVYSAGHATGTTPQKLFVANYSQDVKQFANGFVVRIGAAANSTGTVIISPSTSATIRKIYPAFMLGSSVGNFSDGKMGRFFNHTLVLLPDGCGTLLRAFYCILEPRSGNHCPAGNSYTSFATYHTPATDCSDGNYNRNASLNSFKEYFNLRNCTFMYTYNITEDEILEWFGITQTAQGVHLFSSRYVDLYGGNMFQFATLPVYDTIKYYSIIPHSIRSIQSDRKAWAAFYVYKLQPLTFLLDFSVDGYIRRAIDCGFNDLSQLHCSYESFDVESGVYSVSSFEAKPSGSVVEQAEGVECDFSPLLSGTPPQVYNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVSSAGPISQFNYKQSFSNPTCLILATVPHNLTTITKPLKYSYINKCSRLLSDDRTEVPQLVNANQYSPCVSIVPSTVWEDGDYYRKQLSPLEGGGWLVASGSTVAMTEQLQMGFGITVQYGTDTNSVCPKLEFANDTKIASQLGNCVEYSLYGVSGRGVFQNCTAVGVRQQRFVYDAYQNLVGYYSDDGNYYCLRACVSVPVSVIYDKETKTHATLFGSVACEHISSTMSQYSRSTRSMLKRRDSTYGPLQTPVGCVLGLVNSSLFVE\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198358937779,"sku":"RP01303-10","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198358970547,"sku":"RP01303-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_65c75395-da32-4bd8-a1c7-54615a14c307.png?v=1766961125","url":"https:\/\/afsbio.com\/products\/recombinant-mers-cov-spike-s1-protein-rp01303","provider":"AFSBio Inc.","version":"1.0","type":"link"}