{"product_id":"recombinant-mip-3α-ccl20-human-bk0139","title":"Recombinant MIP-3α\/CCL20, Human - BK0139","description":"Recombinant MIP-3α\/CCL20, Human\n\nCatalogue Numbers: BK0139-5, BK0139-25\n\nSizes: 5μg, 25μg\n\nSource: Escherichia coli\n\nMolecular Weight: 8.0 kDa, observed by reducing SDS-PAGE.\n\nPurity: \u0026gt; 95% as analyzed by SDS-PAGE.\n\nBiological Activity: The EC50 value of humanMIP-3 alpha\/CCL20 on Caˆ2+ mobilization assay in CHO-K1\/Ga15\/hCCR6 cells (human Ga15 and human CCR6 stably expressed in CHO-K1 cells) is less than 200 ng\/ml.\n\nPhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\n\nFormulation: Lyophilized after extensive dialysis against 53mM Na\u003csub\u003e2\u003c\/sub\u003eHPO\u003csub\u003e4\u003c\/sub\u003e, 147 mM NaH\u003csub\u003e2\u003c\/sub\u003ePO\u003csub\u003e4\u003c\/sub\u003e, 300 mM NaCl, pH6.5.\n\nAA Sequence: ASN FDCCLGYTDR ILHPKFIVGF TRQLANEGCD INAIIFHTKK KLSVCANPKQ TWVKYIVRLL SKKVKNM\n\nEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\n\nReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\n\nStorage: Lyophilized recombinant Human MIP- 3α\/CCL20 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, recombinant human MIP-3α\/CCL20 should be stable up to 1 week at 4°C or up to 2 months at -20°C.\n\nUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\n\nDescription: Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family. It is strongly chemotactic for lymphocytes and weakly attracts neutrophils, also known as LARC (Liver and Activation-regulated Chemokine) and as Exodus. It can signal through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors.Recombinant Human MIP-3α\/CCL20 produced in E.coliis a single non-glycosylated polypeptide chain containing 70 amino acids. A fully biologically active molecule, rhMIP-3α\/CCL20has a molecular mass of 8.0 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.","brand":"BioWorld","offers":[{"title":"5μg","offer_id":42882245230771,"sku":"BK0139-5","price":217.41,"currency_code":"CAD","in_stock":true},{"title":"25μg","offer_id":42882245263539,"sku":"BK0139-25","price":375.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_11617154-b9f7-4ba2-bced-49b2b5cd6568.jpg?v=1702049973","url":"https:\/\/afsbio.com\/products\/recombinant-mip-3%ce%b1-ccl20-human-bk0139","provider":"AFSBio Inc.","version":"1.0","type":"link"}