{"product_id":"recombinant-mouse-4-1bb-tnfrsf9-protein-aa-24-187-fc-tagactive-pksm041199","title":"Recombinant Mouse 4-1BB\/TNFRSF9 Protein (aa 24-187, Fc Tag)(Active) - PKSM041199","description":"\u003cp\u003eRecombinant Mouse 4-1BB\/TNFRSF9 Protein (aa 24-187, Fc Tag)(Active)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSM041199-10, PKSM041199-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: 4-1BB; TNFRSF9\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: 4-1BB; A930040I11Rik; AA408498; AI325004; Cd137; CDw137; ILA; Ly63; Secreted CD137 antigen; Tumor necrosis factor receptor superfamily member 9; Tnfrsf9\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Mouse\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eApplication: ELISA\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc\u003c\/p\u003e\n\n\u003cp\u003eAccession: NP_001070976.1\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9\/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Immobilized Human 4-1BBL-His(Cat: PKSH032023) at 0.05μg\/ml(100 μl\/well) can bind Mouse 4-1BB-Fc.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Val24-Leu187\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Not Applicable\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 44.7 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60-70 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice\/gel packs. Upon receipt, store it immediately at \u0026lt; - 20°C.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43114021159091,"sku":"PKSM041199-10","price":359.8,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43114021191859,"sku":"PKSM041199-50","price":625.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_15658c7b-0f52-4a65-b67a-83b5082f45b0.png?v=1709550331","url":"https:\/\/afsbio.com\/products\/recombinant-mouse-4-1bb-tnfrsf9-protein-aa-24-187-fc-tagactive-pksm041199","provider":"AFSBio Inc.","version":"1.0","type":"link"}